Klinefelter's Syndrome: Causes & Symptoms ||Class 12 Biology
Klinefelter's syndrome is a sex chromosomal abnormality. It occurs due to the presence of an additional copy of X chromosome resulting in the karyotype of 47, XXY.
The syndrome was named after American endocrinologist Harry Klinefelter's in 1942, who described about it.
Klinefelter's syndrome occurs randomly. An older mother may have a slightly increased risk of a child with Klinefelter's Syndrome. It is one of the most common chromosomal Disorders, occuring in 1-2 per 1,000 live male birth.
Affected individuals are sterile male. Individuals have masculine development but feminine development (development of breast, i.e., gynaecomastia) also occurs. Sometimes symptoms are more prominent and may include weaker muscles, poor coordination, less body hair and undeveloped testes.
There is no cure for Klinefelter's syndrome, a number of treatment may help. Physical therapy, counseling, speech and language therapy may be useful.
Klinefelter's Syndrome
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